Mild abnormalities in liver histology associated with chronic hepatitis: distinction from normal liver histology.

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Mild abnormalities in liver histology associated with chronic hepatitis: distinction from normal liver histology.

BACKGROUND Chronic hepatitis C virus infection associated with contaminated anti-D immunoglobulin has become an issue of recent concern. The clinical course of chronic hepatitis C infection is unpredictable and histological assessment is felt to be the most reliable means of assessing disease status. Semiquantitative scoring systems have been devised, which assess degree of necroinflammatory di...

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Can Viral Load Predict Liver Histology in Patients With Chronic Hepatitis B?

Introduction: Hepatitis B virus (HBV) infection is a global public health problem. Serum HBV DNA measurement is a non-invasive test that predicts the liver disease progression. The aim of this study was to determine the HBV DNA level and look for a relation between the HBV DNA level and liver histology. Methods: This was a cross sectional study on chronic...

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Relationship between hepatitis B DNA Viral load in the liver and it\'s histology in patient with chronic hepatitis B

Background: Serial measurement of  hepatitis B virus (HBV) DNA levels in the liver and its relation with liver damage and serum HBV DNA levels are guide to begin and/or end a treatment course. This study evaluated the relationship between liver hepatitis B DNA viral load with liver histology in patients with chronic hepatitis B (HBV). Methods:  Thirty patients with chronic anti-Hbe positive ...

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Serum markers of liver fibrogenesis, and liver histology findings in patients with chronic liver diseases.

AIM OF THE STUDY Investigation of the relationships between the grade and stage of chronic liver diseases irrespective of their etiology using some novel serum markers of liver fibrogenesis, the "classical" serum markers of liver necro-inflammatory injury (such as transaminases), and the histomorphological evaluation of liver biopsies. METHODS Markers of liver fibrogenesis: serum metalloprote...

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Liver histology in hepatitis C infection: a comparison between patients with persistently normal or abnormal transaminases.

Forty two cases of confirmed hepatitis C virus (HCV) infection with available liver histology were studied. Most patients, 23 of 42 (55%) had abnormal liver function tests but 19 of 42 (45%) had persistently normal liver transaminases (mean aspartate transaminase (AST) 24.1 IU/l, mean follow up 10 months). Histological examinations in the group with normal AST activities were normal in two of 1...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1997

ISSN: 0021-9746

DOI: 10.1136/jcp.50.11.929